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The Cai Mep container terminals can accommodate vessels with a draught of 15.2 m (50 ft), equivalent to the largest container ships in the world. These mother vessels sail on to Europe or the United States, which signifies that items may be shipped internationally to and from Phnom Penh with only a single transshipment at Cai Mep. As an international river, a number of agreements exist between the countries that share the Mekong to enable trade and passage between them. Agreement on the Cooperation for the Sustainable Development of the Mekong River Basin, Article 9, Freedom of Navigation, 5 April 1995, Chiang Rai. In December 2016, the Thai cabinet of Prime Minister Prayut Chan-o-cha agreed "in principle" to a plan to dredge stretches of the Mekong and demolish rocky outcrops which can be hindrances to simple navigation. The worldwide Lancang-Mekong River navigation improvement plan for 2015-2025, conceived by China, Myanmar, Lao, and Thailand, goals to make the river extra navigable for 500-tonne cargo vessels sailing the river from Yunnan to Luang Prabang, a distance of 890 km (550 mi). China has been the driving drive behind the demolition plan because it goals to broaden trade in the world. The plan is split into two phases. The first part, from 2015 to 2020, involves a survey, a design, and an evaluation of the environmental and social impacts of the project. These need to be approved by the 4 countries involved: China, Laos, Myanmar, Thailand. The second part (2020-2025) involves navigational improvements from Simao in China to 243 border posts in China and Myanmar, a distance of 259 km (161 mi).

Local teams have countered that native inhabitants already function their boats 12 months-round and that the plan to blast the rapids is not about making life better for native folks, however about enabling yr-spherical site visitors of large Chinese industrial boats. On 4 February 2020, the Thai Cabinet voted to stop the mission to blast and dredge ninety seven km (60 mi) of the river bed after Beijing failed to stump up the money for further surveys of the affected area. Construction of Myanmar-Laos Friendship Bridge began on 19 February 2013. The bridge might be 691.6 m (2,269 ft) lengthy and have an 8.5 m (28 ft) large two-lane motorway. The Thai-Lao Friendship Bridge (Thai: สะพานมิตรภาพ ไทย-ลาว, RTGS: Saphan Mittraphap Thai-Lao) connects Nong Khai city with Vientiane in Laos. The 1,170 m-long (3,840 ft) bridge opened on 8 April 1994. It has two 3.5 m-large (11 ft) lanes with a single railway line within the center. On 20 March 2004, the Thai and Lao governments agreed to extend the railway to Tha Nalaeng in Laos. This extension has since been completed. The Second Thai-Lao Friendship Bridge connects Mukdahan to Savannakhet. The Third Thai-Lao Friendship Bridge opened for site visitors on eleven November 2011, connecting Nakhon Phanom Province (Thailand) and Thakhek (Laos), as part of Asian Highway 3. The Chinese and Thai governments agreed to construct the bridge and share the estimated US$33 million cost.

From the purpose the place it rises to its mouth, essentially the most precipitous drop within the Mekong happens in the higher Mekong basin, a stretch of some 2,200 km (1,four hundred mi). Here, it drops 4,500 m (14,800 ft) earlier than it enters the decrease basin the place the borders of Thailand, Laos, China, and Myanmar come together in the Golden Triangle. Downstream from the Golden Triangle, the river flows for a further 2,600 km (1,600 mi) by Laos, Thailand, and Cambodia before entering the South China Sea through a complex delta system in Vietnam. The higher basin makes up 24% of the entire space and contributes 15-20% of the water that flows into the Mekong River. The catchment here is steep and slim with Soil erosion being a serious drawback and because of this, roughly 50% of the sediment within the river comes from the higher basin. In Yunnan Province in China, the river and its tributaries are confined by narrow, deep gorges. The tributary river systems in this a part of the basin are small. Only 14 have catchment areas that exceed 1,000 km2 (four hundred sq mi), yet the greatest quantity of lack of forest cowl in your complete river system per square kilometer has occurred in this region because of heavy unchecked demand for natural resources. Within the south of Yunnan, in Simao and Xishuangbanna Prefectures, the river changes because the valley opens out, the floodplain turns into wider, and the river becomes wider and slower. Major tributary programs develop in the lower basin. These techniques might be separated into two teams: tributaries that contribute to the foremost wet season flows, and tributaries that drain low relief areas of lower rainfall.